Analyzing immunogenomic predictors of ICI response in biliary tract cancer

Immunogenomic profiling identifies prognostic markers but limited ICI efficacy in BTC

INDICATION
Biliary Tract Cancer

Somatic landscape: overall BTC and actionable alterations across subtypes

 

 

The 15 most commonly altered genes across all patients are shown. The table shows the prevalence of targetable drivers across BTC subtypes.

 

Related cases

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Abstract data visualization showing a grid of blue, black, and brown dots in patterns.

TP53 mutations are enriched in HER2-positive biliary tract cancer and drive poor outcomes

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Biliary Tract Cancer
TP53
HER2
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Abstract grid of squares showing color gradients and clustered data points.

Shorter Pluvicto treatment course for patients with prostate cancer and high initial PSA

PSA
Prostate
Icon with three vertical bars and a circle, resembling a bar graph or LinkedIn logo.Lens Library
Visualization showing multiple rows of blue and orange squares, divided by a black dotted line.

Genomic and transcriptomic differences between early-onset and non-early-onset PDAC

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Pancreatic
KRAS
BRCA2
SMAD4
CDKN2A