Molecular and clinical characterization of HER2-low versus HER2-0 breast cancer

Comparison of genomic profiles and survival outcomes between HER2-low and HER2-0 subtypes

INDICATION
Breast
BIOMARKER
HER2

 

 

Top: ERBB2 RNA expression in HER2-0, HER2-low, and HER2+ patients. Bottom: UMAP of mutation data (excluding ERBB2) colored by HER2-0, HER2-low, or HER2+ status, utilizing the Tempus xT 648-gene panel. Analysis is restricted to considering the presence of pathogenic alterations.