Tempus Reports Third Quarter 2024 Results and Agreement to Acquire Ambry Genetics

Nov 04, 2024
Press Release

CHICAGO, November 4, 2024 — Tempus AI, Inc. (NASDAQ: TEM), a technology company leading the adoption of AI to advance precision medicine and patient care, today reported financial results for the quarter that ended September 30, 2024. The company also announced that it has entered into an agreement to acquire Ambry Genetics, a leader in genetic testing that aims to improve health by understanding the relationship between genetics and disease.

 

  • Revenue increased 33.0% year-over-year to $180.9 million in the third quarter of 2024
  • Data and services revenue growth accelerated to 64.4% year-over-year
  • Genomics unit growth accelerated to 23.9% annually with rising average revenue per clinical test
  • Net Loss of $(75.8 million), which included $22.2 million of stock compensation expense and related employer payroll taxes
  • Adjusted EBITDA improved $14.4 million year over year to $(21.8 million)
  • Expect full year 2024 revenue of ~$700 million, which represents ~32% annual growth

 

For additional information on the quarter, including a letter from our CEO and CFO, please visit our investors relations site at investors.tempus.com.

 

“The overall business performed well in the quarter, as demonstrated by accelerating volume growth in our genomics business and accelerating revenue growth in our data and services business, specifically within Insights,” said Eric Lefkofsky, Founder and CEO of Tempus. “We’re also excited to announce the pending acquisition of Ambry Genetics, which broadens our testing portfolio, expands our disease coverage, and enhances the types of products we can offer to our biotech and pharmaceutical partners. In addition, Ambry is uniquely positioned given that its revenues are currently growing at north of 25% a year and it generates meaningful EBITDA and cash flow.”

 

Third Quarter 2024 Financial Results

 

Three months ended September 30, 2024
20242023
(in thousands, except percentages)
GAAP Results
Revenue$180,929$136,057
Genomics gross margin48.4%51.9%
Data and services gross margin76.8%60.5%
Operating expenses$159,455$118,816
Net loss$(75,840)$(53,426)
Non-GAAP Results
Non-GAAP Genomics gross margin49.3%51.9%
Non-GAAP Data and services gross margin78.3%60.5%
Non-GAAP Operating Expenses$139,284$118,816
Adjusted EBITDA$(21,843)$(36,206)

 

(1). Not meaningful due to the impact of including stock compensation expense and related employer payroll taxes

 

  • Genomics revenue of $116.4 million in the third quarter of 2024, an increase of $19.6 million or 20.3% over the third quarter of 2023, with 23.9% unit growth.
  • Data and services revenue of $64.5 million in the third quarter of 2024, an increase of $25.3 million or 64.4% over the third quarter of 2023.
  • Non-GAAP Genomics gross margin was 49.3% in the third quarter of 2024, compared to 51.9% in the third quarter of 2023, largely related to one-time cash payments in 2023.
  • Non-GAAP Data and services gross margin was 78.3% in the third quarter of 2024, compared to 60.5% in the third quarter of 2023, led by Insights, or data licensing revenue, which grew 86.6% year over year.
  • Net Loss of $(75.8 million), which included $22.2 million of stock compensation and related employer payroll taxes compared to net loss of $(552.2 million) in the second quarter of 2024, including $493.1 million of stock compensation and related employer taxes and net loss of $(53.4 million) in the third quarter of 2023.
  • Adjusted EBITDA $(21.8 million) in the third quarter of 2024, compared to $(31.2 million) in the second quarter of 2024, and $(36.2 million) in the third quarter of 2023.
  • Ending cash and marketable securities were $466.3 million.

 

Additional Operating Highlights

 

  • Announced a multi-year first of its kind collaboration with BioNTech to leverage Tempus’ TCR dataset in support of BioNTech’s next-generation oncology pipeline.
  • Announced a 3 year extension with Merck EMD at the culmination of our last 3 year strategic agreement.
  • Initiated a collaboration with OneOncology to bring more biomarker-driven trials to patients in the community setting at scale.
  • Initiated the beta launch of our patient-facing app, Olivia, an AI-enabled personal health locker that empowers individuals to holistically organize, store, and manage their own health data through our generative AI healthcare concierge.

 

Ambry Genetics Acquisition

 

Tempus today announced that it has entered into an agreement to acquire Ambry Genetics, a leader in genetic testing. Under the terms of the agreement, Tempus will pay $375 million in cash and $225 million in shares at closing, of which $100 million will be subject to a lock-up agreement until one year post-transaction close. The deal is expected to be financed in part through a $300 million increase in short and long term debt provided by Ares, Tempus’ current lender. Ambry expects to generate >$300 million in revenue in calendar year 2024 and EBITDA of >$40 million. For more information on Ambry and its impact, see Tempus’ latest investor deck.

 

Ambry is a leader in hereditary cancer screening and currently serves as Tempus’ main reference lab in this category. The acquisition will provide Tempus with expanded testing capabilities for inherited cancer risk. These services are becoming more and more important for healthcare professionals navigating critical medical decisions with cancer patients and their relatives.

 

In addition to expanding and enhancing the company’s hereditary screening portfolio, the acquisition of Ambry will complement Tempus’ strategy of using data to advance clinical and scientific innovation. Ambry’s extensive product offerings will also allow Tempus to expand into new disease categories, including pediatrics, rare disease, immunology, women’s reproductive health, and cardiology.

 

Financial Outlook and Guidance

 

Tempus continues to expect full year 2024 revenue of approximately $700 million, which represents approximately 32% year-over-year growth and approximately ($105 million) in adjusted EBITDA, an improvement of approximately $50 million over 2023.

 

Webcast and Conference Call Information

 

A conference call and webcast will begin today, November 4, 2024 after market close at 4:30 p.m. Eastern Time. Interested parties may access details at:

 

 

The webcast may be accessed on the company’s investor relations website at investors.tempus.com. For those unable to listen to the live webcast, a recording will be made available on the company’s website after the event and will be accessible for one year. Visit the investor relations website to find the company’s latest deck, and commentary on the quarter by Eric Lefkofsky, Founder and CEO and Jim Rogers, CFO, which will be discussed on the conference call and webcast.

 

About Tempus

 

Tempus is a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare. With one of the world’s largest libraries of multimodal data, and an operating system to make that data accessible and useful, Tempus provides AI-enabled precision medicine solutions to physicians to deliver personalized patient care and in parallel facilitates discovery, development and delivery of optimal therapeutics. The goal is for each patient to benefit from the treatment of others who came before by providing physicians with tools that learn as the company gathers more data. For more information, visit tempus.com.

 

Non-GAAP Financial Measures

 

In addition to the financial information presented in this release in accordance with accounting principles generally accepted in the United States of America (GAAP), Tempus also presents adjusted non-GAAP financial measures.

 

Non-GAAP gross profit is defined as GAAP gross profit, excluding stock-based compensation expense and employer payroll tax related to stock-based compensation (collectively, the “stock-based compensation adjustments”). Non-GAAP gross margin is defined as gross profit, excluding the stock-based compensation adjustments, as a percentage of revenue. Non-GAAP operating expenses are calculated as the sum of technology research and development expense, research and development expense, and selling, general and administrative expense, excluding the stock-based compensation adjustments. Non-GAAP net income (loss) is defined as net income (loss), adjusted to exclude (i) losses on equity method investments, (ii) changes in fair value of our warrant liability, warrant asset, marketable equity securities, contingent consideration liabilities and indemnity-related holdback liabilities, (iii) the payment of $2.3 million of our Series G-4 convertible preferred stock in connection with the initial public offering (the “G-4 Special Payment”), and (iv) amortization of deferred other income from our IP License Agreement with SB Tempus. Non-GAAP net income (loss) per share is defined as adjusted net income (loss) divided by weighted average common shares outstanding, basic and diluted.

 

EBITDA is defined as net income (loss), adjusted to exclude (i) interest income, (ii) interest expense, (iii) depreciation and amortization, and (iv) provision for (benefit from) income taxes. Adjusted EBITDA is defined as net income (loss), adjusted to exclude (i) interest income, (ii) interest expense, (iii) depreciation and amortization, (iv) provision for (benefit from) income taxes, (v) losses on equity method investments, (vi) changes in fair value of our warrant liability, warrant asset, marketable equity securities, contingent consideration liabilities and indemnity-related holdback liabilities, (vii) stock-based compensation expense, (viii) employer payroll tax related to stock-based compensation expense, (ix) the G-4 Special Payment, and (x) amortization of deferred other income from our IP License Agreement with SB Tempus. Adjusted EBITDA margin is calculated as adjusted EBITDA as a percentage of revenue.

 

Tempus believes these non-GAAP financial measures are useful to investors and others because they allow for additional information with respect to financial measures used by management in its financial and operational decision-making and they may be used by institutional investors and the analyst community to help them analyze the health of Tempus’ business. In particular, Adjusted EBITDA is a key measurement used by Tempus management to make operating decisions, including those related to analyzing operating expenses, evaluating performance, and performing strategic planning and annual budgeting. However, there are a number of limitations related to the use of non-GAAP financial measures, and these non-GAAP measures should be considered in addition to, not as a substitute for or in isolation from, our financial results prepared in accordance with GAAP. Other companies, including companies in our industry, may calculate these non-GAAP financial measures differently or not at all, which reduces their usefulness as comparative measures.

 

Tempus does not provide guidance for net loss, the most directly comparable GAAP measure to EBITDA and Adjusted EBITDA, and similarly cannot provide a reconciliation between Ambry’s forecasted EBITDA and its net income (loss) or between Tempus’ forecasted Adjusted EBITDA and net loss without unreasonable effort due to the unavailability of reliable estimates for certain components of net income (loss) and the respective reconciliations. These forecasted items are not within Tempus’ or Ambry’s control, as applicable, may vary greatly between periods and could significantly impact future financial results.

 

Forward Looking Statements

 

This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended (the “Securities Act”), and Section 21E of the Securities Exchange Act of 1934, as amended, about Tempus, Ambry and their respective industries that involve substantial risks and uncertainties. All statements other than statements of historical facts contained in this press release are forward-looking statements, including, but not limited to, Tempus’ expected financial results for full year 2024 and Ambry’s expected financial results for calendar year 2024; the contributions of Tempus’ research and findings to the larger scientific community, the use of Tempus’ products and services to advance clinical care for patients, and the pending acquisition of Ambry. In some cases, you can identify forward-looking statements because they contain words such as “anticipate,” “believe,” “contemplate,” “continue,” “could,” “estimate,” “expect,” “going to,” “intend,” “may,” “plan,” “potential,” “predict,” “project,” “should,” “target,” “will,” or “would” or the negative of these words or other similar terms or expressions. Tempus cautions you that the foregoing may not include all of the forward-looking statements made in this press release.

 

You should not rely on forward-looking statements as predictions of future events. Tempus has based the forward-looking statements contained in this press release primarily on its current expectations and projections about future events and trends that it believes may affect Tempus’ business, financial condition, results of operations and prospects. These forward-looking statements are subject to risks and uncertainties related to: the intended use of Tempus’ products and services; Tempus’ financial performance; the ability to attract and retain customers and partners; managing Tempus’ growth and future expenses; competition and new market entrants; compliance with new laws, regulations and executive actions, including any evolving regulations in the artificial intelligence space; the ability to maintain, protect and enhance Tempus’ intellectual property; the ability to attract and retain qualified team members and key personnel; the ability to repay or refinance outstanding debt, or to access additional financing; future acquisitions, divestitures or investments, including our ability to consummate the acquisition of Ambry Genetics and the related financing on the terms described herein or at all and, if consummated, to realize the expected benefits of such acquisition; the potential adverse impact of climate change, natural disasters, health epidemics, macroeconomic conditions, and war or other armed conflict, as well as risks, uncertainties, and other factors described in the section titled “Risk Factors” in Tempus’ Form 10-Q for the quarter ended June 30, 2024 filed with the Securities and Exchange Commission (“SEC”) on August 6, 2024, pursuant to Rule 424(b)(4) under the Securities Act, as well as in other filings Tempus may make with the SEC in the future, including its Quarterly Report on Form 10-Q for the quarter ended September 30, 2024. In addition, any forward-looking statements contained in this press release are based on assumptions that Tempus believes to be reasonable as of this date. Tempus undertakes no obligation to update any forward-looking statements to reflect events or circumstances after the date of this press release or to reflect new information or the occurrence of unanticipated events, except as required by law.

 

Advisors

 

TD Cowen served as the sole financial advisor representing Tempus in the purchase of Ambry Genetics. Morgan Stanley, J.P. Morgan, and Allen & Company LLC represented the company in security financing.

 

Contacts

 

Tempus Communications
Erin Carron
media@tempus.com

 

Tempus Investor Relations
Elizabeth Krutoholow
elizabeth.krutoholow@tempus.com

 

Source: Tempus AI, Inc.

 


 

Tempus AI, Inc.
Condensed Consolidated Statements of Operations and Comprehensive Loss
(unaudited)
(in thousands, except per share amounts)

 

Three Months Ended September 30,Nine Months Ended September 30,
20242023
Net revenue
Genomics$116,422
Data and services64,507
Total net revenue$180,929
Cost and operating expenses
Cost of revenues, genomics60,216
Cost of revenues, data and services14,964
Technology research and development30,680
Research and development27,348
Selling, general and administrative101,427
Total cost and operating expenses234,545
Loss from operations$(53,616)
Interest income4,789
Interest expense(13,761)
Other (expense) income, net(11,522)
Loss before provision for income taxes$(74,110)
Provision for income taxes(38)
Losses from equity method investments(1,692)
Net loss$(75,840)
Dividends on Series A, B, B-1, B-2, C, D, E, F, G, G-3, and G-4 preferred shares
Cumulative Undeclared Dividends on Series C preferred shares
Net loss attributable to common shareholders, basic and diluted(75,840)
Net loss per share attributable to common shareholders, basic and diluted$(0.46)
Weighted-average shares outstanding used to compute net loss per share, basic and diluted165,612
Comprehensive Loss, net of tax
Net loss$(75,840)
Foreign currency translation adjustment10,302
Comprehensive loss$(65,538)

 


 

Tempus AI, Inc.
Condensed Consolidated Balance Sheets
(unaudited)
(in thousands, except share and per share amounts)

 

September 30, 2024December 31, 2023
Assets
Current Assets$388,006
Cash and cash equivalents 
Accounts receivable, net of allowances of $1,154 and $1,115 at September 30, 2024 and December 31, 2023, respectively145,616
Inventory36,138
Warrant asset 
Prepaid expenses and other current assets31,335
Marketable equity securities78,317
Deferred offering costs
Total current assets$679,412
Property and equipment, net 59,392
Goodwill73,365
Warrant asset, less current portion
Intangible assets, net 14,289
Investments and other assets8,692
Investment in joint venture103,699
Warrant contract asset, less current portion17,866
Operating lease right-of-use assets14,141
Restricted cash872
Total Assets$971,728
 
Liabilities, Convertible redeemable preferred stock, and Stockholders’ equity (deficit)
Current liabilities
Account payable 49,027
Accrued expenses101,985
Deferred revenue67,604
Deferred other income15,955
Other current liabilities9,913
Operating lease liabilities5,894
Accrued data licensing fees 2,242
Accrued dividends
Total current liabilities$252,620
Operating lease liabilities, less current portion26,664
Convertible promissory note 174,460
Warrant liability 76,900
Other long-term liabilities15,403
Interest payable66,529
Long-term debt, net 264,527
Deferred other income, less current portion27,921
Deferred revenue, less current portion12,976
Total Liabilities$918,000
 
Commitments and contingencies (Note 8)
Convertible redeemable preferred stock, $0.0001 par value, no and 69,803,765 shares authorized at September 30, 2024 and December 31, 2023, respectively; no and 63,525,953 shares issued and outstanding at September 30, 2024 and December 31, 2023, respectively; aggregate liquidation preference of $0 and $1,130,429 at September 30, 2024 and December 31, 2023, respectively
 
Stockholders’ equity (deficit)
Class A Voting Common Stock, $0.0001 par value, 1,000,000,000 and 200,228,024 shares authorized at September 30, 2024 and December 31, 2023, respectively; 150,280,363 and 58,367,961 shares issued and outstanding at September 30, 2024 and December 31, 2023, respectively$15
Class B Voting Common Stock, $0.0001 par value, 5,500,000 and 5,374,899 shares authorized at September 30, 2024 and December 31, 2023, respectively; 5,043,789 and no shares issued and outstanding at September 30, 2024 and December 31, 2023, respectively1
Non-voting Common Stock, $0.0001 par value, no and 66,946,627 shares authorized at September 30, 2024 and December 31, 2023, respectively; no shares issued and outstanding at September 30, 2024, and 5,205,802 shares issued and 5,060,336 shares outstanding at December 31, 2023 
Treasury Stock, 145,466 shares at September 30, 2024 and December 31, 2023, at cost(3,602)
Additional Paid-In Capital2,184,926
Accumulated Other Comprehensive (Loss) Income10,208
Accumulated deficit(2,137,820)
Total Stockholders’ equity (deficit)$53,728
Total Liabilities, Convertible redeemable preferred stock, and Stockholders’ equity (deficit)$971,728

 


 

Tempus AI, Inc.
Condensed Consolidated Statements of Cash Flows
(unaudited)
(in thousands, except per share amounts)

 

Nine Months Ended September 30,
 
Operating activities
Net loss
Adjustments to reconcile net loss to net cash used in operating activities
Change in fair value of warrant liability
Stock-based compensation
Gain on warrant exercise
Gain on marketable equity securities
Amortization of original issue discount
Amortization of deferred financing fees
Change in fair value of contingent consideration
Amortization of warrant contract asset
Depreciation and amortization
Provision for bad debt expense
Change in fair value of warrant asset
Loss from equity-method investments
Amortization of finance right-of-use lease assets
Non-cash operating lease costs
Minimum accretion expense
Impairment of intangible assets
PIK interest added to principal
Change in assets and liabilities
Accounts receivable 
Inventory
Prepaid expenses and other current assets
Investments and other assets
Accounts payable
Deferred revenue
Deferred other income
Accrued data licensing fees
Accrued expenses & other
Interest payable
Operating net liabilities
Net cash used in operating activities
 
Investing activities
Purchases of property and equipment
Proceeds from sales of marketable equity securities
Business combinations, net of cash acquired (Note 4)
Investment in joint venture
Purchases of marketable equity securities
Net cash provided by (used in) investing activities
(34,768)
 
Financing activities
Proceeds from issuance of common stock in connection with initial public offering, net of underwriting discounts and commissions
Tax withholding related to net share settlement of restricted stock units
Issuance of Series G-5 Preferred Stock
Principal payments on finance lease liabilities
Purchase of treasury stock
Payment of deferred offering costs
Dividends paid
Proceeds from long-term debt, net of original issue discount
Payment of indemnity holdback related to acquisition
G-4 Special Payment
Net cash provided by financing activities
Effect of foreign exchange rates on cash
Net increase (decrease) in Cash, Cash Equivalents and Restricted Cash
Cash, cash equivalents and restricted cash, beginning of period
Cash, cash equivalents and restricted cash, end of period
Cash, Cash Equivalents and Restricted Cash are Comprised of:
Cash and cash equivalents
Restricted cash and cash equivalents
Total cash, cash equivalents and restricted cash
Supplemental disclosure of cash flow information
Cash paid during the year for interest
Cash paid for income taxes
 
Supplemental disclosure of noncash investing and financing activities
Dividends payable
Purchases of property and equipment, accrued but not paid
Deferred offering costs, accrued but not yet paid
Redemption of convertible promissory note
Non-voting common stock issued in connection with business combinations
344
Operating lease liabilities arising from obtaining right-of-use assets
Conversion of redeemable convertible preferred stock to common stock in connection with initial public offering
Taxes related to net share settlement of restricted stock units not yet paid
Reclassification of deferred offering costs to additional paid-in capital upon initial public offering
Issuance of Series G-3 Preferred Stock
Issuance of Series G-4 Preferred Stock

 


 

**Tempus AI, Inc.
**Reconciliation of GAAP to Non-GAAP Financial Measures
(unaudited)
(in thousands, except percentages and per share amounts)

 

Genomics Gross Profit & Gross Margin

 

 Three Months Ended September 30,Nine Months Ended September 30,
 
 20242023
Genomics revenue$116,422
Cost of revenues, genomics 60,126
Gross profit, genomics$56,296
Stock-based compensation expense 1,083
Employer payroll tax related to stock-based compensation 26
Non-GAAP gross profit, genomics$57,405
 
Genomics gross margin48.4%
Stock-based compensation expense 0.9%
Employer payroll tax related to stock-based compensation0.0%
Non-GAAP gross margin, genomics 49.3%

 


 

Data and Services Gross Profit & Gross Margin

 

 Three Months Ended September 30,Nine Months Ended September 30,
 
 20242023
Data and services revenue$64,507
Costs of revenues, data and services 14,964
Gross profit, data and services$49,543
Stock-based compensation expense 916
Employer payroll tax related to stock-based compensation 43
Non-GAAP gross profit, data and services$50,502
 
Gross margin, data and services 76.8%
Stock-based compensation expense 1.4%
Employer payroll tax related to stock-based compensation 0.1%
Non-GAAP gross margin, data and services 78.3%

 


 

Total Gross Profit & Gross Margin

 

 Three Months Ended September 30,Nine Months Ended September 30,
 
 20242023
Net revenue$180,929
Costs of revenues 75,090
Gross profit$105,839
Stock-based compensation expense 1,999
Employer payroll tax related to stock-based compensation 69
Non-GAAP gross profit $107,907
 
Gross margin 58.5%
Stock-based compensation expense 1.1%
Employer payroll tax related to stock-based compensation 0.0%
Non-GAAP gross margin 59.6%

 


 

Operating Expenses

 

 Three Months Ended September 30,Nine Months Ended September 30,
 
 20242023
Technology research and development$30,680
Stock-based compensation expense 3,929
Employer payroll tax related to stock-based compensation192
Non-GAAP technology research and development$26,559
 
Research and development$27,348
Stock-based compensation expense2,554
Employer payroll tax related to stock-based compensation134
Non-GAAP research and development$24,660
 
Selling, general and administrative$101,427
Stock-based compensation expense 12,556
Employer payroll tax related to stock-based compensation806
Non-GAAP selling, general and administrative$88,065
 
Operating expenses$159,455
Stock-based compensation expense19,039
Employer payroll tax related to stock-based compensation1,132
Non-GAAP operating expenses139,284

 


 

Earnings per Share

 

 Three Months Ended September 30, 2024Nine Months Ended September 30, 2024
 
Net loss$(75,840)
Fair market changes(1) 15,605
Stock-based compensation expense21,038
Employer payroll tax related to stock-based compensation from IPO1,201
G-4 Special Payment – 
Amortization of technology license (3,989)
Non-GAAP net loss$(41,985)
Non-GAAP net loss per share$(0.25)
Weighted average common shares outstanding, basic and diluted165,612

 

(1). Fair value changes include gains and losses related to quarterly fair value adjustments of our warrant liability, warrant asset, marketable equity securities, contingent consideration liabilities, and indemnity-related holdback liabilities.

 


 

Adjusted EBITDA

 

 Three Months Ended September 30,Nine Months Ended September 30,
 
 20242023
Net loss$(75,840)
Interest income (4,789)
Interest expense13,761
Depreciation6,788
Amortization 2,652
Provision for income taxes38
EBITDA$(57,390)
Loses on equity method investments 1,692
Fair market changes(1)15,605
Stock-based compensation expense21,038
Employer payroll tax related to stock-based compensation 1,201
G-4 Special Payment
Amortization of technology license(3,989)
Adjusted EBITDA$(21,843)

 

(1). Fair value changes include gains and losses related to quarterly fair value adjustments of our warrant liability, warrant asset, marketable equity securities, contingent consideration liabilities, and indemnity-related holdback liabilities.