Prognostic impact of TP53 hotspot mutations across solid tumors

Specific TP53 hotspot mutations predict worse real-world survival across multiple cancers

INDICATION
Pan-Cancer
BIOMARKER
TP53

Dot plot showing log10(HR) for six TP53 hotspot mutations across cancer indications.
Forest plot with multivariate Cox PH model Hazard-Ratio estimates assessing rwOS in patients with specific TP53 hotspot mutation by indication.

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