Evaluating MTAP deletion and immune profile scores to identify unmet needs in solid tumors

Real-world data reveals MTAP deletions enrich for lower immune profile scores and worse outcomes

INDICATION
Pan-Cancer
BIOMARKER
IPS
MTAP

Scatter plot showing MTAP deletion prevalence and co-occurrence in IPS high cancer.

 

Co-occurrence likelihood (log odds ratio; x-axis) between MTAP deletion and IPS-high patients by MTAP deletion prevalence (y-axis) across solid tumor indications. Dot size indicates total count of MTAP deletion for each cancer type. Included samples required at least 40% tumor purity.