ATM expression as a predictive biomarker for first-line treatment outcomes in metastatic CRC

ATM expression levels show differential survival outcomes for mCRC patients in 1L therapy

INDICATION
Colorectal
BIOMARKER
ATM

Kaplan-Meier curve comparing survival probability between ATM-High and ATM-Low groups.
Kaplan-Meier curves show ATM-Low group with better survival probability than ATM-High (p=0.016).
Kaplan-Meier survival curves comparing rwOS between ATM-low and ATM-high CRC patients in 1L FOLFIRI (N=716) (A) and 1L FOLFOX (N=2,679) (B) pre-treated samples. Shaded areas represent the 95% confidence intervals. Median survival times are specified. Cohort split on median expression level.

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