High WRN expression and immunotherapy outcomes in MSI-H/dMMR colorectal cancer

Determining the impact of WRN expression on immunotherapy response in MSI-H/dMMR CRC patients

INDICATION
Colorectal
BIOMARKER
MSI-H/dMMR

 

Kaplan-Meier survival curves comparing rwPFS for WRN-High and WRN-Low expressors, in pre-treatment samples from CRC patients treated with IO mono or IO+Chemo combinations in 1L. Shaded areas represent the 95% confidence intervals. Median survival times (months) are specified. Median WRN expression was used to derive WRN-High/Low groups. Log-Rank test P value is indicated.

 

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