Impact of PIK3R1 loss-of-function on survival in metastatic breast cancer

Evidence-based insights into the poor prognosis of PIK3R1-altered breast cancer

INDICATION
Breast
BIOMARKER
PIK3R1

 

Kaplan-Meier survival curves comparing rwOS between PIK3R1-alt and PIK3R1-wt patients. Shaded areas represent the 95% confidence intervals. Median survival times are specified. Cohort split on median expression level.

 

*alt group includes any PIK3R1 LoF P/LP SNV or Indel or Copy Number deletions (CN: 0). (Time = Months).