Stratifying HR+ HER2- breast cancer through ER signaling and G2/M molecular signatures

Molecular signatures improve patient stratification beyond standard IHC clinical markers

INDICATION
Breast
BIOMARKER
ER Signaling

 

Kaplan-Meier survival curves comparing groups of high/low ER signaling activity and high/low G2/M (proliferation) checkpoint activity. Progression as event. No risk set adjustment performed. Median survival times (months) are specified.