Transcriptional and immune signatures of ESR1 and PIK3CA co-mutations in HR+ MBC

Discovery of distinct immunosuppressive microenvironments to guide combination therapies

INDICATION
Breast
BIOMARKER
ESR1

Related cases

Grid of orange, blue, purple, and green square blocks with scattered black dots.

Mutational profiles and treatment resistance in metastatic TNBC

2026-03-27
Breast
PIK3CA
Abstract digital pattern with scattered black, blue, green, and purple dots on a white background.

Stratifying HR+ HER2- breast cancer through ER signaling and G2/M molecular signatures

2026-03-27
Breast
ER Signaling
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Impact of PIK3R1 loss-of-function on survival in metastatic breast cancer

2026-03-06
Breast
PIK3R1