9p21 loss and low interferon expression predict poor ICI response in NSCLC

RWD analysis links combined 9p21 loss and low IFNK expression to ICI resistance in NSCLC

INDICATION
Lung

Immune infiltration in CMdel and CMwt NSCLC by IFNK expression status

 

 

CMdel samples with high IFNK expression have increased infiltrate of multiple cell types, including (A) M1 macrophages and (B) CD8 T cells, but decreased (C) neutrophil infiltrate.

 

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