Defining high-risk LUAD subtypes with large-scale RWD

RWD analysis identifies six LUAD subtypes, including a high-risk group with poor outcomes

INDICATION
Lung

The molecular C5 subtype exhibits the poorest prognosis among LUAD patients

 

 

(a) Kaplan-Meier survival curves showing rwPFS from the start of index treatment (metastatic line of therapy [LOT] 1) to the first progression event. (b) Distribution of LOT1 therapy groups across LUAD subtypes. (c) Forest plot showing multivariate CoxPH analysis, controlling for clinical confounders.