John Axerio-Cilies is Chief Data Technology Officer at Tempus AI, leading data platform and engineering teams focused on scalable, secure, and efficient systems to advance Tempus’s commercial data strategy and applications. Previously, as SVP and Head of AI Apps Engineering, he oversaw product and engineering in genomics algos, digital pathology, radiology, cardiology, and generative AI, integrating diverse data types to address disease-specific care gaps and support clinical trial enrollment. Earlier roles included General Manager of Radiology at Tempus, where he combined medical imaging with clinical and molecular data to support multimodal precision medicine, and CEO and co-founder/CTO of Arterys, where he and his team pioneered groundbreaking AI innovations such as 4D Flow MRI, cloud-native 4D rendering and the first FDA cleared deep learning algorithm in healthcare.