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LIFE SCIENCES

The operating system for precision medicine 2.0

One comprehensive platform that offers biopharma speed, scale, and integrated solutions for all lifecycle stages.

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Click the boxes below to learn more about how Tempus is advancing precision medicine throughout the drug lifecycle

  • Research

    Help de-risk and accelerate the path to clinic

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  • Clinical Development

    Boost confidence at each developmental milestone

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  • Commercialization

    Understand and take action on real-world experience

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Research

Help de-risk and accelerate the path to clinic

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Disease Biology

Uncover deeper insights regarding tumor heterogeneity, resistance mechanisms, and interaction within the tumor microenvironment to support targeted development strategies. Integrate tumor organoid models, multimodal data, multi-omic profiling, and AI-driven analytics to map oncogenic pathways, characterize immune evasion strategies, and identify tumor vulnerabilities.

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AI and Drug Screening
Drug screening with advanced imaging capabilities

Learn how noninvasive imaging techniques allow for continuous study of organoids.
Characterizing Unmet Needs

Leverage real-world data and epidemiological modeling to quantify disease burden and survival disparities, helping uncover potential resistance-associated biomarkers and high-impact subpopulations. Evaluate treatment gaps through real-world evidence to guide development prioritization.

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Research Characterizing Unmet Needs
Bristol Myers Squibb Collaboration

Identifying and validating targets with multimodal data, computation, and patient-derived models.
Clinical Trial Design
Real-world Outcomes & Value
Target Validation & Lead Optimization

Explore a target’s involvement in cancer progression and therapeutic actionability. Assess target expression, function, and druggability using tumor organoid models to evaluate its biological relevance. Leverage real-world toxicity, resistance, and treatment-response data to further validate targets and refine drug candidates.

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QA A deep dive into the science and significance of Tempus Immune Profile Score IPS
Validating Immune Profile Score (IPS)

Dr. Michelle Ting-Lin, discusses the science behind a novel biomarker and ICI prognosticator.
Biomarker Strategy

Validate and refine biomarkers using tumor organoids and multimodal data to assess predictive, prognostic, or pharmacodynamic utility. Leverage insights generated to optimize patient stratification and response monitoring throughout clinical development.

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QA Advancing immunotherapy biomarker identification with Immune Profile Score IPS
Advancing immunotherapy biomarker identification

Jason Blue-Smith discusses IO biomarker challenges and how Tempus IPS provides solutions.
Clinical Trial Execution
Care Gaps Closure
Novel Target Identification

Investigate possible novel target candidates while considering oncogenic dependencies via high-throughput functional screening. Refine candidate selection using computational modeling and AI-powered omics solutions to predict druggability, pathway redundancy, and tumor specificity. Investigate therapeutic relevance of emerging targets through validation studies using tumor organoid models, enabling a data-based prioritization of first-in-class or best-in-class therapeutic approaches.

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QA Harnessing AI with multimodal data to transform drug development
Harnessing AI with multimodal data

Dr. Kate Sasser, PhD, discusses layering ML and AI on RWD to drive insights in drug discovery.
Indication Selection

Identify tumor types and patient populations that may benefit from a therapeutic candidate by integrating disease biology, biomarker insights, and clinical unmet needs. Refine clinical development strategies to support efficient resource allocation and increase the probability of technical success.

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Clin Dev Clinical Trial Design and Indication Selection
Revolutionize drug screening

How Tempus AI’s imaging enables continuous organoid study across assays, preserving testing viability.
IUO Validation & CDx Development
Clinical Development

Boost confidence at each developmental milestone

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Disease Biology
Characterizing Unmet Needs
Clinical Trial Design

Analyze contemporaneous, real-world, multimodal data to characterize tumor heterogeneity, enabling the integration of those insights into trial I/E criteria. Refine trial endpoints to improve the probability of technical success and effectively evaluate drug efficacy across diverse patient populations. Assess the impact of different methods for generating standard-of-care performance data as comparators.

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Strategically simulate and contextualize data

Mirati leverages Tempus RWD to revise its KRAS strategy and refine patient selection.
Real-world Outcomes & Value
Target Validation & Lead Optimization
Biomarker Strategy

Leverage multimodal data to refine biomarker-driven patient selection criteria and optimize trial design for regulatory review. Integrate biomarker assays into clinical trial workflows to help maximize the probability of technical success and accelerate the path toward CDx submission.

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Case Study AstraZeneca reduces time to launch
Reduce time to launch with multimodal data

Learn how AstraZeneca simplified its approach to TROPION-Lung01 and drove down time to launch.
Clinical Trial Execution

Optimize site selection and leverage real-world data for feasibility assessments. Tap into an extensive provider network equipped with algorithmic patient-matching workflows to accelerate enrollment. Execute clinical trials efficiently by leveraging data-driven insights.

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Case Study Sermonix TIME Program
Activate trial sites faster

Sermonix was able to accelerate timelines for first patient in and enrollment by working with Tempus.
Care Gaps Closure
Novel Target Identification
Indication Selection

Explore multimodal datasets and leverage AI-driven analytics to investigate indications with high unmet need. Implement a strategic approach to indication selection informed by tumor heterogeneity across subpopulations and standard of care landscape dynamics to help optimize resource allocation, accelerate time to market, and expand label opportunities.

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Clin Dev Clinical Trial Design and Indication Selection
PAVO: Assessing the safety and efficacy of niraparib (PARPi)

Accelerating clinical trial start-up and execution with an end-to-end approach.
IUO Validation & CDx Development

Delve into real-world data to understand biomarker prevalence and utilize comprehensive genomic profiling to support IDE studies. Establish robust analytical and clinical validation studies, aligning CDx development strategies with therapeutic trial timelines. All on a broadly distributed platform.

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Case Study A2 Biotherapeutics with CDx
Enhance clinical development with Tempus’ CDx platform

A2 Biotherapeutics uses HLA-LOH as a biomarker to progress breakthrough cell therapy.
Commercialization

Understand and take action on real-world experience

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Disease Biology
Characterizing Unmet Needs
Clinical Trial Design
Real-world Outcomes & Value

Synthesize a comprehensive view of each patient and population. Evaluate therapeutic safety, efficacy, and long-term benefits with integrated clinical, molecular, claims, and outcomes data. Generate RWE to assist regulatory decision-making, inform HEOR, and facilitate reimbursement negotiations.

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Case Study NSCLC
Get more insights faster with multimodal data

Tempus collaborates with Pfizer to further profile HER2 expression across various cancers.
Target Validation & Lead Optimization
Biomarker Strategy
Clinical Trial Execution
Care Gaps Closure

Leverage an AI-enabled care pathway platform that empowers providers to deliver the next step in a patient’s care journey. Integrate RWE into clinical strategies to help bridge gaps in early diagnosis, treatment adherence, and long-term patient outcomes.

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Case Study Pfizer HER2 Expression
Closing biomarker testing gaps for early-stage NSCLC patients

TriHealth Cancer and Blood Institute surfaces and closes care gaps with Next.
Novel Target Identification
Indication Selection
IUO Validation & CDx Development
  • 8.5M+

    de-identified research records

  • 600+

    direct data connections across 3K+ health institutions

  • 10

    NGS tests to support clinical trial and research sequencing

  • 7.5K+

    oncologists

  • 60+

    care gap modules launched

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Explore our customer success stories to see why Tempus is a trusted partner for 95% of the top 20 pharma companies* and more than 200 biopharma companies.

AstraZeneca

Learn how AstraZeneca integrated Tempus data and tools across their Oncology R&D governance process.

Read Case study

Mirati Therapeutics

Make quicker decisions by simulating and contextualizing data with Tempus

Read Case study

Recursion

Advancing biomarker-driven therapeutic development with a data-first approach

Read press release

Pfizer

Furthering profile HER2 expression across various cancers with multimodal data

Read Case study

Sermonix

Patient recruitment

Read article

Bristol Myers Squibb

Identify new targets and validate them faster and with higher confidence using multimodal datasets, computational approaches, and patient-derived disease models in specific cancer disease areas

Read Press release

BioNTech

A collaboration to generate novel insights into the biological mechanisms supporting the discovery of new cancer therapeuitcs

Read Press release

GSK

Leveraging diagnostics and data to drive next-generation drug development

Watch webinar

Eisai

The evolution of RWE and HEOR

Read article

Stemline Therapeutics, Inc.

Closing ESR1 testing gaps with an AI-enabled care pathway intelligence platform

Read Press release

MD Anderson Cancer Center

ADCs in focus: The next generation of precision medicine in oncology

Watch webinar

JW Pharmaceutical

Applying real-world data and biological modeling to enhance early research and development

Read press release

Takeda

Leveraging multimodal real-world datasets and biological model systems in oncology R&D

Read Press release

Remix Therapeutics

Interrogating specific cohorts with real-world datasets

Read Press release

United Therapeutics

Develop and investigate AI-based medical device software to detect patients at risk of having undiagnosed pulmonary hypertension (PH)

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IFLI

Derive AI-driven insights to accelerate the development of follicular lymphoma treatments in an effort to improve patient outcomes

Read Press release

TScan

Partner to develop assays

Read press release

Aadi Bioscience

Accelerate trial enrollment

Read case study

AstraZeneca

Increasing Probability of Technical Success (PTS)

Read blog

Gilead

RWD and decision making

Read article

AstraZeneca

Multimodal data for Probability of Technical Success (PTS)

Watch webinar

Kronos Bio

RWE for drug development

Read article

AstraZeneca

Clinical trials for novel therapies

Read press release

Actuate Therapeutics

Use liquid biopsy and RUO DNA Methylation to discover and validate

Read press release

Gilead

Biomarker innovation

Watch webinar

Sermonix

Accelerating tiral enrollment in ELAINE II

Read case study

A2 Bio

NGS to power R&D

Read article

AstraZeneca and Pfizer

Data-driven CDx development

Read article

TScan

RWD and immuno-oncology

Read article

GSK

Using data and AI/ML to achieve precision medicine

Watch article

Janssen

Using RWD

Read article

GSK

Intersection of genomics and machine learning

Read press release

Kartos Therapeutics

Progressing the goal of innovative therapies

Read press release

Eli Lilly

Increasing accessibility to testing

Read press release

Geisinger

AI and ECG

Read blog

Genmab

Multimodal RWD

Read article

Janssen

Leveraging AI/ML for RWD

Read press release

AstraZeneca

Strategic collaboration

Read press release

Kronos Bio

Collaboration around data and organoids

Read press release

Bristol Myers Squibb

Discover RNA based targets

Read press release

Genmab

Discover new targets

Read press release

Kronos

Advancing transcriptional cancer therapies with comprehensive life science solutions

Read Case study
Our Impact

Thanks to Tempus, we are able to identify patients that can be helped with our proprietary TMod™ platform. Without them, we wouldn’t be able to do this.

William Go, SVP, Head of Development at A2 Biotherapeutics (TMod™ is a trademark of A2 Biotherapeutics)

Our Impact

Tempus is a leader in the field of personalized medicine, and like Genmab, Tempus has a mission to improve the lives of cancer patients. We are looking forward to expanding our exciting partnership with them and to the possibility of discovering important new oncology targets and biomarkers.

Jan van de Winkel, Ph.D., Chief Executive Officer of Genmab

Learn more about our partnership with Genmab
Our Impact

Bayer’s strong focus in precision medicine combined with Tempus’ unique testing offering has culminated in this collaboration to bring genomic testing to cancer patients.

Bhavesh Ashar, Senior Vice President, Head of U.S. Oncology at Bayer

Learn more about our partnership with Bayer
Our Impact

[Working with Tempus Data] gives you more confidence in the drug as you’re designing a study… it helped us understand what patients are going on 2nd line and benefitting from docetaxel vs. those patients who are not benefitting.

LEORA HORN, MD, Global Clinical Head for Lung Cancer & Lung Cancer Strategy. AstraZeneca

Learn more about our partnership with AstraZeneca

Explore by Solution

  1. Sequencing

    Use our genomic platform to prospectively sequence through clinical trials and retrospectively support research priorities.
  2. Data Collaborations

    Leverage real-world datasets of matched molecular and clinical data with digital whole slide pathology images to uncover new insights across the research and development spectrum.
  3. Biological Modeling

    Leverage our vast tumor organoid repository to accelerate drug discovery.
  4. Companion Diagnostics

    Integrate CDx claims into Tempus assays through a validated and established sequencing platform to pursue companion diagnostic biomarkers.
  5. Omics Solutions

    Discover unique molecular targets, track methylation patterns, and build multimodal datasets with our robust suite of high throughput multi-omic solutions.

  6. Clinical Research Organization Services

    Bring discoveries from the lab to market through our full-service CRO.
  7. Clinical Trial Enrollment

    Utilize NGS and EMR integrations to identify patients that match your study's eligibility criteria, including targetable biomarkers from DNA and RNA.
  8. Tempus Studies

    Leverage our end to end solutions to design and execute Tempus-sponsored clinical trials for therapeutics, devices, and diagnostics from study concept to registrational filing.
  9. Care Gap Solutions

    Timely AI-enabled notifications to accelerate adoption of precision care pathways and avoid gaps in care.
  10. AI-enabled Algorithms

    Harness multimodal data, AI/machine learning (ML), and bioinformatics to help develop, validate, and deploy molecular algorithms.

Featured Resources

View all RESOURCES
  • UPCOMING WEBINAR:

    Transforming R&D with Generative AI and Real-World Data

    Leaders from Tempus and Erasca, Inc. discuss the transformative power of AI in oncology research and drug development. Watch their conversation from the AACR Annual Meeting 2025.

    Watch now
  • UPCOMING WEBINAR:

    Bridging the translational gap: The role of organoids in oncology R&D

    Explore the evolving role of organoids in oncology R&D. This white paper discusses their potential as predictive preclinical models to reduce translational risk and accelerate the development of precision medicine.

    Read more
  • UPCOMING WEBINAR:

    The RNA advantage: A multimodal approach to accelerating oncology R&D

    Discover how integrating multi-omics data and AI is transforming oncology drug development in our recent webinar. Learn about RNA sequencing’s role in companion diagnostics and how Tempus Loop supports target identification and validation.

    Watch replay
  • UPCOMING WEBINAR:

    Q&A: Harnessing generative AI to refine clinical research & drug development

    Leaders from Tempus and Cedars-Sinai discuss how generative AI is refining clinical research. Learn how Tempus Lens helps researchers accelerate insights by analyzing complex, unstructured real-world data.

    Read more
  • UPCOMING WEBINAR:

    Q&A: Connecting real-world data and organoids through Tempus Loop

    Learn how Tempus Loop connects real-world data with patient-derived organoids. Tim Hagerty, VP of Life Science Strategy, explains how this integrated approach accelerates target identification and validation in oncology.

    Read more
  • UPCOMING WEBINAR:

    Q&A: How cutting-edge technologies are helping to advance precision medicine

    In this Q&A, Tempus leaders discuss how AI and machine learning are transforming precision medicine. Learn how applications like Tempus Lens use generative AI to streamline data analysis and accelerate research for scientists.

    Read more
  • UPCOMING WEBINAR:

    Development of a clinical algorithm to prognosticate response to immunotherapy

    Discover how Tempus developed the Immune Profile Score (IPS), an AI-driven algorithm providing prognostic insights for ICI therapy. This case study details the methodology, real-world validation, and impact on precision oncology.

    Read more
  • UPCOMING WEBINAR:

    Evolving outcomes research: The convergence of data, technology, and collaboration

    This white paper examines the evolving field of outcomes research, focusing on integrating real-world data and advanced analytics. Explore innovative approaches that are transforming research and driving the development of patient-centric healthcare solutions.

    Read more
  • UPCOMING WEBINAR:

    Oncology innovation: How emerging biotechs lead through RWD & AI

    Tempus’ COO discusses how biotechs can use RWD and AI to accelerate oncology drug development. Discover data-driven strategies to streamline clinical trials, optimize patient selection, and improve decision-making.

    Read more

*Based on publicly available 2022 segment revenue

Trusted by hundreds of biopharma to power drug development

The information on this page is intended for life sciences companies and focuses on research and development applications.

Discover AI-enabled precision medicine

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